Immunoglobulin M antibodies to hepatitis B core antigen: evaluation of enzyme immunoassay for diagnosis of hepatitis B virus infection

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occult hepatitis b virus infection among blood donors with antibodies to hepatitis b core antigen

diagnosis of hepatitis b is routinely based on of serological assay of hepatitis b surface antigen (hbsag). occult hepatitis b virus (hbv) infection is generally defined as the detection of hbv -dna in the serum or tissues of subjects who have negative test for hbsag. transmission of hbv infection has been documented from hbsag negative, anti-hbc positive blood and organ donors. the aim of this...

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Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen.

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Occult Hepatitis B Virus Infection among Blood Donors with Antibodies to Hepatitis B Core Antigen

Diagnosis of hepatitis B is routinely based on of serological assay of hepatitis B surface antigen (HBsAg). Occult hepatitis B virus (HBV) infection is generally defined as the detection of HBV -DNA in the serum or tissues of subjects who have negative test for HBsAg. Transmission of HBV infection has been documented from HBsAg negative, anti-HBc positive blood and organ donors. The aim of this...

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Significance of Hepatitis B Core Antibody as the Only Marker of Hepatitis B Virus Infection in High Risk Patients

  Background and Objective: Presence of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is defined, as isolated anti-HBc. little is known about the clinical significance of the isolated anti-HBc in hepatitis B virus (HBV) infections. The aim of this study was to assess the significance of anti-HBc as the onl...

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Evaluation of diagnostic efficiency of the new enzyme immunoassay for detection of IgM antibodies to Hepatitis B core antigen

Introduction Recently, many studies are available about the detection of viral DNA in sera containing IgM to HBcAg in the absence of HBsAg, which lead to increase the risk of transmission of HBV, what is especially important for blood transfusion and the use of blood products. In this regard, it is important to use highly sensitive ELISA test for detection of IgM against HBcAg which could help ...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1981

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.13.4.618-626.1981